Describe the process of bone remodeling

Describe the process of bone remodeling and its importance in maintaining skeletal integrity and calcium homeostasis. How do osteoclasts and osteoblasts coordinate to remove old bone tissue and deposit new bone matrix, respectively? Additionally, what factors regulate bone remodeling, such as mechanical loading, hormonal influences (e.g., parathyroid hormone and calcitonin), and nutritional status?

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