Explore the anatomical and physiological basis of gastrointestinal motility disorders

Explore the anatomical and physiological basis of gastrointestinal motility disorders such as irritable bowel syndrome (IBS) and gastroparesis, incorporating an analysis of smooth muscle function, enteric nervous system dysfunction, and alterations in gut microbiota composition. Discuss how dysregulated gut-brain communication contributes to symptomatology and potential therapeutic interventions targeting neurotransmitter modulation and gut microbiome manipulation.