How does the dynamic interplay between the gut microbiome, immune system, and central nervous system

How does the dynamic interplay between the gut microbiome, immune system, and central nervous system influence the bidirectional gut-brain axis, and what are the implications for mental health disorders such as depression, anxiety, autism spectrum disorders, and neurodevelopmental conditions, and how can microbiome-targeted interventions, including probiotics, dietary modifications, and fecal microbiota transplantation, offer promising avenues for therapeutic intervention?