How does the hypothalamus integrate temperature signals

Discuss the physiological mechanisms underlying the regulation of body temperature, including thermoregulatory processes such as vasodilation, vasoconstriction, sweating, and shivering. How does the hypothalamus integrate temperature signals from thermoreceptors in the skin and core body tissues to initiate autonomic and behavioral responses aimed at maintaining thermal equilibrium? Furthermore, how do factors like fever, heat acclimatization, and cold adaptation influence thermoregulatory mechanisms and the body’s response to environmental temperature changes?