How does the hypothalamus release corticotropin-releasing hormone
Can you explain the role of the hypothalamic-pituitary-adrenal (HPA) axis in the body’s response to stress and the regulation of cortisol secretion? How does the hypothalamus release corticotropin-releasing hormone (CRH), which stimulates the anterior pituitary gland to produce adrenocorticotropic hormone (ACTH), leading to cortisol synthesis and release from the adrenal glands? Additionally, how does negative feedback control maintain homeostasis by regulating cortisol levels and preventing prolonged activation of the stress response?
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